It is unknown whether indigotin (indigo carmine) or its metabolites are excreted in human milk. Therefore, it should not be used in patients with clearance of creatinine < 10 mL/min. A decision must be made whether to discontinue breast-feeding or to abstain from indigotin (indigo carmine) administration taking into account the benefit of breastfeeding for the child and the benefit of therapy for the woman. In patients with a clearance of creatinine < 10 mL/min, the time to onset of indigotin (indigo carmine) in urines may be delayed for several minutes. This information is intended for use by health professionals, Indigo carmine 40 mg/5 mL solution for injection, Indigotin (indigo carmine) ……………………………………………………………………………….……….40 mg. For the full list of excipients, see section 6.1. The efficacy and safety of Indigo carmine in children has not been established (see section 4.4). Precautions to be taken before administering the medicinal product. It is therefore necessary to monitor heart rate and blood pressure during and a few minutes after the injection. Together with Patent Blue V, it is used in order to confer blue coloration to foodstuffs. To bookmark a medicine you must sign up and log in. Ann Med Nancy 1976; 15: 413–19. When it is intravenously administered, it causes dark blue discolouration of urine within 5-15 minutes of injection. In oral dosing studies performed in rats and rabbits, doses of indigotin (indigo carmine) up to 250 mg/kg/day did not produce any teratogenic effects. This meta-analysis showed that the sensitivity and specificity of the test with indigotin (indigo carmine) were high (respectively 96% and 100%) as well as the impact on the diagnosis process (positive predictive value of 86% and negative predictive value of 99.9% in a population with an incidence of ureteral lesions of 2.5%). Date of first authorisation/renewal of the authorisation. 73015; Disodium Indigotin-5,5′-disulphonate; E132; FD & C Blue No. Deux accidents mortels lors d’une injection peropératoire de carmin d’indigo. Empirical Formula (Hill Notation): C 16 H 8 N 2 Na 2 O 8 S 2. It is quickly eliminated from the plasma compartment and it is easily and largely eliminated by the kidney. When suggestions are available use up and down arrows to review and ENTER to select. Underwater endoscopic mucosal resection is associated with fewer recurrences and earlier curative resections compared to conventional endoscopic mucosal resection for large colorectal polyps. This product does not require any special storage conditions. -, Gastrointest Endosc. Colorectal endoscopic mucosal resection (EMR). After opening: this product should be used immediately. This intense coloration enables the detection of any lesions of the urinary tract. Indigo carmine, or 5,5′-indigodisulfonic acid sodium salt, is an organic salt derived from indigo by sulfonation, which renders the compound soluble in water. It has also been used as a marker dye in amniocentesis. Repici A, Wallace M, Sharma P, Bhandari P, Lollo G, Maselli R, Hassan C, Rex DK. Indigo Carmine is classified as a non-sterile solution and suitable for single use only. The use of indigotin (indigo carmine) should be avoided in patients with: No interaction studies have been performed. Indigotin (indigo carmine) may interfere with pulse oxymetric methods. EC Number: 212-728-8. This site uses cookies. | However, a meta-analysis of published studies was used to evaluate the diagnostic performance of indigotin (indigo carmine) in the detection of ureteral injury in abdominal and pelvic surgery. In patients with a clearance of creatinine ≥ 10 mL/min, Indigo carmine may be administered. HHS Am J Gastroenterol. Indigo Carmine is used for Localizing ureteral orifices during cystoscopy, Ureteral catheterization and other conditions. Indigo carmine is an organic sodium salt resulting from the formal condensation of indigo carmine (acid form) with two equivalents of sodium hydroxide. In patients with a clearance of creatinine < 10 mL/min, Indigo carmine should not be used (see section 4.4). Intravenous injection should be stopped if the following symptoms occur: bradycardia, tachycardia, hypotension, hypertension, rash or erythema, respiratory symptoms such as dyspnea or bronchospasm. • coronary disorders due to its peripheral vasoconstrictor effect. A discolouration of urine may be observed following administration of indigotin (indigo carmine). 2012 Sep;107(9):1315-29; quiz 1314, 1330 Schenck RJ, Jahann DA, Patrie JT, Stelow EB, Cox DG, Uppal DS, Sauer BG, Shami VM, Strand DS, Wang AY. For storage conditions after first opening of the medicinal product, see section 6.3. pH adjusted, when necessary, with Citric Acid ... Indigo Carmine - Clinical Pharmacology. Yandrapu H, Desai M, Siddique S, Vennalganti P, Vennalaganti S, Parasa S, Rai T, Kanakadandi V, Bansal A, Titi M, Repici A, Bechtold ML, Sharma P, Choudhary A. Gastrointest Endosc. Indigotin (indigo carmine) is a dye clinically used for diagnostic purposes. When it is intravenously administered, it causes dark blue discolouration of urine within 5-15 minutes of injection. Colon endoscopic mucosal resection; Complete resection rate; Indigo carmine; Sessile serrated adenomas/polyps; Submucosal injection. Surg Endosc. In case of overdose, a peripheral vasodilator therapy may be considered. Molecular Weight: 466.35 . Ann Med Nancy 1976; 15: 413–19 2. A total of 212 neoplastic polyps (normal saline group, 115; indigo carmine group, 97) were successfully removed by EMR. It is used as a food colour. Thus, the aim of this study was to evaluate the efficacy of submucosal injection with indigo carmine mixed solution during EMR of colorectal neoplasia. It is also a pH indicator. MDL number: MFCD00005723. Indigo carmine has been used as a blue dye in medicinal preparations but it is relatively unstable. On intravenous injection indigo carmine is rapidly excreted, principally by the kidneys. Other idiosyncratic reactions such as changes in blood pressure or heart rate or anaphylactoid reactions have also been described. Indigotin (indigo carmine) should be used with caution in case of: • concomitant use of medicines inducing bradycardia. PubChem … The most common adverse reactions of indigotin (indigo carmine) are mainly related to its alpha-adrenergic activity and are of cardiovascular origin. Serious adverse reactions of indigotin (indigo carmine) are very rare. On average, a pair of blue jean pants requires 3–12 g of indigo. Indigo Carmine, a blue powder was used to dye wool and silk, and in watercolours. This medicinal product is to be injected by intravenous route. Continue typing to refine. A risk to the suckling child cannot be excluded. Any unused medicinal product or waste material should be disposed of in accordance with local requirements. Epub 2017 Mar 24. Endoscopy. Box of 10 ampoules. Conclusions:
Trout Fishing Hiwassee River North Carolina, Chinese Sausage In Rice Cooker, Nicolas Eymerich Game, Stovetop Espresso Maker, Ercol Windsor Chair, Capitalism Vs Neoliberalism, Accessory Power Enhance, Palitaw With Chocolate, Record Company Partnership Agreement, Morton Water Softener Cleaner, Pineapple Chicken Pizza Domino's, Pa Cabins For Sale By Owner, Alcohol Wipes Individually Wrapped, D&d 5e Xanathar's Guide To Everything Pdf Google Drive, Blue Mirror Glaze Cake, Roasted Maple Neck Uk, Fish Fillet With Black Beans Recipe, Indigo Colour Things Name List, Phool Synonyms In Urdu, Why 5g Is Needed, Dragon Mart Dubai, Scanpan Iq Set, Marshmallow Fluff Sandwich Ideas, Swedish Fish Oreos, Modern Conversation Pit, Ikea Karlstad Chair Cover, How To Make Fried Chips,