Hiroaki Itoh, Kensuke Miura, Koichi Kamiya, Tomoya Yamashita, Masayuki Inoue. Gerui Ren, Qinheng Zheng, and Hua Wang . Annie Tam, Matthew B. Soellner, Ronald T. Raines. Click reactions in protein chemistry: from the preparation of semisynthetic enzymes to new click enzymes. -Diazides and Their Direct Conversion into Safe Materials. ; Raines, R.T. Org. Sorry, your blog cannot share posts by email. Roberto Morán-Ramallal, Ramón Liz, and Vicente Gotor. Bioorthogonale Chemie - oder: in einem Meer aus Funktionalität nach Selektivität fischen. Evaluation and optimisation of unnatural amino acid incorporation and bioorthogonal bioconjugation for site-specific fluorescent labelling of proteins expressed in mammalian cells. Rapid Cross-Metathesis for Reversible Protein Modifications via Chemical Access to Se-Allyl-selenocysteine in Proteins. Design, synthesis, and biological evaluation of novel alkenylthiophenes as potent and selective CB1 cannabinoid receptor antagonists. Synthesis and Micropatterning of Photocatalytically Reactive Self-Assembled Monolayers Covalently Linked to Si(100) Surfaces via a Si–C Bond. Targeted Identification of Glycosylated Proteins in the Gastric Pathogen Synthetic, Zwitterionic Sp1 Oligosaccharides Adopt a Helical Structure Crucial for Antibody Interaction. Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity. S. David Tilley, Neel S. Joshi, Matthew B. Francis. ・Gololobov, Y. G.; Kasukhin, L. F. Tetrahedron 1992, 48, 1353. doi:10.1016/S0040-4020(01)92229-X Divergent Synthesis of Photoaffinity Probe Candidates by Click Reactions of Azido-Substituted Aryltrifluoromethyldiazirines. In the Staudinger reaction, azide compounds react with phosphines to form iminophosphorane species, which can be hydrolyzed to give primary amines. From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions. D. Vasudevan. Younggyu Kim, Sam O. Ho, Natalie R. Gassman, You Korlann, Elizabeth V. Landorf, Frank R. Collart and Shimon Weiss . Rutjes, Otto C. Boerman. Boran‐Addukte von Stickstoffwasserstoffsäure und Organischen Aziden: Intermediate bei der Bildung von Aminoboranen. Soc. Suvi H. M. Rajamäki, Lidia De Luca, Francesca Capitta, Andrea Porcheddu. Bioorthogonal labelling of biomolecules: new functional handles and ligation methods. Reference: J. Org. Development and Applications of the Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) as a Bioorthogonal Reaction. Phosphine-Based Redox Catalysis in the Direct Traceless Staudinger Ligation of Carboxylic Acids and Azides. Yuqi Wang, Ruibing An, Zhiliang Luo, Deju Ye. 2004, 69, 4299. Ellen M. Sletten and Carolyn R. Bertozzi . Lucia De Rosa, Alessandra Romanelli, Luca Domenico D'Andrea. Comparison of Reductive Ligation‐Based Detection Strategies for Nitroxyl (HNO) and Jia Pan, Jonathan A. Rapid Oxime and Hydrazone Ligations with Aromatic Aldehydes for Biomolecular Labeling. Hemanta Baruah, Sujiet Puthenveetil, Yoon-Aa Choi, Samit Shah, Alice Y. Ting. Juhua Xu, Amanda J DeGraw, Benjamin P Duckworth, Stepan Lenevich, Cheng-Min Tann, Emily C Jenson, Simon J Gruber, George Barany, Mark D Distefano. It holds the crucial characteristics for bioorthogonal chemistry: biocompatibility, select … Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins. S Probes, and Fast Strain‐promoted Azide‐Alkyne Cycloaddition and Staudinger Reactions. Facile Formation of Dehydroalanine From S-Nitrosocysteines. N These findings establish a platform for optimizing the Staudinger ligation for expanded use in biological applications. The Staudinger ligation of azides and phosphines has found widespread use in the field of chemical biology, but the mechanism of the transformation has not been characterized in detail. Boron azides in Staudinger oxidations and cycloadditions. Exploiting the Substrate Tolerance of Farnesyltransferase for Site-Selective Protein Derivatization. Disulfide Competition for Phosphine Gold(I) Thiolates: Phosphine Oxide Formation vs. Thiolate Disulfide Exchange. Bioconjugation via azide–Staudinger ligation: an overview. Reaction Mechanism and Kinetics of the Traceless Staudinger Ligation. Mild and Chemoselective Peptide-Bond Cleavage of Peptides and Proteins at Azido Homoalanine. Synthesis of coumarin or ferrocene labeled nucleosides via Staudinger ligation. Johan Hygum Dam, Gyorgyi Osztrovszky, Lars Ulrik Nordstrøm, Robert Madsen. Ethyl ester and silyl ester of imidodiphosphate: An alternative route to access phosphorus-nitrogen-phosphorus bonds via Staudinger reaction. Synthesis, conformations and guest-encapsulation ability. Di Lu, Guangwei Lv, Zhiyuan Xu, Yixin Dong, Xiaofei Ji. Marjoke F. Debets, Jan C. M. van Hest, Floris P. J. T. Rutjes. Re-examination of Dynamics of Polyeletrolytes in Salt-Free Dilute Solutions by Designing and Using a Novel Neutral−Charged−Neutral Reversible Polymer. Organic Azides: An Exploding Diversity of a Unique Class of Compounds. Zhipeng A. Wang, Yadagiri Kurra, Xin Wang, Yu Zeng, Yan‐Jiun Lee, Vangmayee Sharma, Hening Lin, Susie Y. Dai, Wenshe R. Liu. Thiago de Sousa Fonseca, Marcos Reinaldo da Silva, Maria da Conceição Ferreira de Oliveira, Telma Leda Gomes de Lemos, Ricardo de Araújo Marques, Marcos Carlos de Mattos. Anomalous Staudinger reaction at intramolecular frustrated P–B Lewis pair frameworks. Copper(II)-Catalyzed Direct Azidation of Studies toward the synthesis of macrotermycin C: stereoselective construction of the acyclic skeleton of the aglycon. One-Pot Catalytic Synthesis of ... Several variations on the basic procedure, described above, exist. Multifluorinated Aryl Azides for the Development of Improved H Chim. A Proline-Based Phosphine Template for Staudinger Ligation. Roque. N Catalytic Staudinger—Vilarrasa Reaction for the Direct Ligation of Carboxylic Acids and Azides. Pamela V. Chang, Jennifer A. Prescher, Ellen M. Sletten, Jeremy M. Baskin, Isaac A. Miller, Nicholas J. Agard, Anderson Lo, Carolyn R. Bertozzi. First phosphine imine-forming reaction is conducted involving treatment of the azide with the phosphine. 3 Chemoselektive Ligations- und Modifikationsstrategien für Peptide und Proteine. Highly diastereo- and enantioselective organocatalytic synthesis of new heterocyclic hybrids isoindolinone-imidate and isoindolinone-phthalide. Constantin Mamat, Matthew Gott, Jörg Steinbach. Adib Charafeddine, Wissam Dayoub, Hubert Chapuis, Peter Strazewski. Annika Stute, Lukas Heletta, Roland Fröhlich, Constantin G. Daniliuc, Gerald Kehr, Gerhard Erker. Erik Oude Blenke, Gruson Klaasse, Hannes Merten, Andreas Plückthun, Enrico Mastrobattista, Nathaniel I. Martin. Staudinger Ligation as a Method for Bioconjugation. the Altmetric Attention Score and how the score is calculated. Jinbo Li, Hao Kong, Lei Huang, Bo Cheng, Ke Qin, Mengmeng Zheng, Zheng Yan. Hongzhi Cao, Yanhong Li, Kam Lau, Saddam Muthana, Hai Yu, Jiansong Cheng, Harshal A. Chokhawala, Go Sugiarto, Lei Zhang, Xi Chen. Expanding the scope of chemoselective peptide ligations in chemical biology. The Collective Power of Genetically Encoded Protein/Peptide Tags and Bioorthogonal Chemistry in Biological Fluorescence Imaging. For permission to reproduce, republish and Aurélien Godinat, Hacer Karatas, Ghyslain Budin, Elena A. Dubikovskaya. Qingju Zhang, Ana Gimeno, Darielys Santana, Zhen Wang, Yury Valdés-Balbin, Laura M. Rodríguez-Noda, Thomas Hansen, Li Kong, Mengjie Shen, Herman S. Overkleeft, Vicente Vérez-Bencomo, Gijsbert A. van der Marel, Jesús Jiménez-Barbero, Fabrizio Chiodo. Chelsea G. Gordon, Carolyn R. Bertozzi. ・Kohn, M.; Breinbauer, R. Angew. Light-Activated Staudinger–Bertozzi Ligation within Living Animals. Direct Measurement of Cathepsin B Activity in the Cytosol of Apoptotic Cells by an Activity-Based Probe. Antonia Di Mola, Francesco Scorzelli, Guglielmo Monaco, Laura Palombi, Antonio Massa. Christian P. R. Hackenberger, Dirk Schwarzer. International Journal of Chemical Kinetics. Acta 1919, 2, 635. Traceless Staudinger Ligation of Glycosyl Azides with Triaryl Phosphines: Stereoselective Synthesis of Glycosyl Amides. Robert V. Kolakowski,, Ning Shangguan,, Ronald R. Sauers, and. Caihong Zhang, Tyler D. Biggs, Nelmi O. Devarie-Baez, Shaomin Shuang, Chuan Dong, Ming Xian. N Kevin Bläsing, Jonas Bresien, René Labbow, Dirk Michalik, Axel Schulz, Max Thomas, Alexander Villinger. FLP reactivity of [Ph Lisa Shah, Scott T. Laughlin, and Isaac S. Carrico . J.S. Organocatalytic Mitsunobu Reactions Julian Tu, Dennis Svatunek, Saba Parvez, Albert C. Liu, Brian J. Levandowski, Hannah J. Eckvahl, Randall T. Peterson, Kendall N. Houk, Raphael M. Franzini. Andrea Niederwieser, Anne-Katrin Späte, Long Duc Nguyen, Christian Jüngst, Werner Reutter, Valentin Wittmann.
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